Vitamin B12 Toxicity


Although vitamin B12 toxicity is uncommon, it is possible to develop side effects while taking the vitamin. Potential side effects include diarrhea, feelings of swelling over the entire body, blood clots in the legs, and signs of an allergic reaction. Although the risk for toxicity is low (even with high doses), you should report any possible side effects to your doctor.

 Signs of Vitamin B12 Toxicity

 There are no signs of vitamin B12 toxicity, per se. There are a few rarely reported side effects that might be attributable to the vitamin, but such side effects are not necessarily related to the dose. These possible side effects include: 


•Blood clots in the legs

•Feelings of swelling over the entire body

•Signs of an allergic reaction, such as:  

◦Hives or a rash


◦Swelling of the lips, mouth, or throat

◦Wheezing or other difficulty breathing.

 What Causes Toxicity?

 Vitamin B12 toxicity is due to an obvious cause — taking too much. The Recommended Dietary Allowance for vitamin B12 for adults ranges from 2.4 to 2.8 mcg daily, depending on several factors. For nutrients that can cause toxicity, a “Tolerable Upper Intake Level” (UL) is given. This is the maximum that can be taken from all sources, including the diet, without causing significant toxicity. There are no UL values for vitamin B12, since the risk of toxicity is quite low.

 Final Thoughts on Vitamin B12 Toxicity

 Vitamin B12 is usually considered a non-toxic substance. Even taking it by injection at high doses does not seem to increase the risk for toxicity. However, if you think you are experiencing vitamin B12 toxicity, let your doctor know. Also, let him or her know if you develop something that “just does not seem right.” While it may not be related to toxicity with vitamin B12, your doctor will be able to diagnose and treat the problem.

After the shots….. (Vaccinations may hurt a little…but disease can hurt a lot!)


 Vaccinations may hurt a little…but disease can hurt a lot!

Your child may need extra love and care after getting vaccinated. Some vaccinations that protect children from serious diseases also can cause discomfort for a while. Here are answers to questions many parents have after their children have been vaccinated. If this post doesn’t answer your questions, call your doctor.

What to do if your child has discomfort

I think my child has a fever. What should I do?

Check your child’s temperature to find out if there is a fever. An easy way to do this is by taking a temperature in the armpit using an electronic thermometer (or by using the method of temperature-taking your doctor recommends). If your child has a temperature that your doctor has told you to be concerned about or if you have questions, call your doctor.

Here are some things you can do to help reduce fever:

  • Give your child plenty to drink.
  • Dress your child lightly. Do not cover or wrap your child tightly.
  • Give your child a fever- or pain-reducing medicine such as acetaminophen or ibuprofen. The dose you give your child should be based on your child’s weight and your doctor’s instructions. Recheck your child’s temperature after 1 hour. Call your doctor if you have questions.

 My child has been fussy since getting vaccinated. What should I do?

 After vaccination, children may be fussy because of pain or fever. To reduce discomfort, you may want to give your child a medicine such as acetaminophen or ibuprofen. If your child is fussy for more than 24 hours, call your doctor.

 My child’s leg or arm is swollen, hot, and red. What should I do?

  • Apply a clean, cool, wet washcloth over the sore area for comfort.
  • For pain, give a medicine such as acetaminophen or ibuprofen
  • If the redness or tenderness increases after 24 hours, call your doctor.

 My child seems really sick. Should I call my doctor?

If you are worried at all about how your child looks or feels, call your doctor immediately.


Anti-Depressants Linked to Suicide


There is an obvious growing trend in our society toward taking antidepressant drugs. So it came as a surprise to many supporters when research showed a potential link between taking antidepressant drugs and suicide. For those who openly support the use of antidepressant drugs, they argue that antidepressant drugs are in fact not linked to suicide, but rather the increase in depressed individuals has made the suicide rate increase.

For those who believe that antidepressants do have the potential to cause people to commit suicide, they argue that research can prove their point by showing that there is an obvious increase in suicidal acts when people are taking antidepressants. They also argue that while there are studies that prove that certain drugs reduce the risk of suicide, they are ignoring the fact that the same medication could produce suicidal actions or behaviors in others.

 Antidepressant drugs such as Fluoxetine, Fluvoxamine and Paroxetine are selective serotonin reuptake inhibitors, commonly known as SSRIs. Serotonin is one of your brain’s most important biochemicals; it controls everything from appetite to mood swings. If you’re depressed, compulsively eating or gambling, not sleeping properly or even just moody, you’re probably lacking serotonin.

 In Health and Nutrition Secrets, Dr. Russell L. Blaylock writes, “It is also known that these medications increase brain levels of the neurotransmitter serotonin, which, in high concentrations, can also act as an excitotoxin.” When antidepressant drugs raise serotonin to an excitotoxin level, the brain reacts in ways similar to mental illness. According to Burton Goldberg’s book, ‘Alternative Medicine’, side effects of SSRIs include uncontrollable facial and body tics, dizziness, hallucinations, nausea, sexual dysfunction, addiction, electric-shock-like sensations in the brain and, of course, homicidal or suicidal thoughts and behavior.

 Unfortunately, the doctors prescribing these SSRIs often forget that you can have too much of a good thing — that is, too much serotonin — so they prescribe SSRIs to just about everyone.

 The experts speak out on antidepressant drugs and suicide:

 ”A lawsuit contends the manufacturer of the popular anti-depressant Paroxetine concealed evidence that the drug can be addictive. The lawsuit was filed on behalf of 35 people from around US who say they suffered symptoms ranging from electrical shocks to suicidal thoughts after discontinuing use of the drug. Paxil is the second largest selling anti-depressant in America. In June of 2001, a jury in Wyoming awarded $8 million in damages to a family of a man after determining that Paroxetine caused him to kill his wife, daughter, and granddaughter before he committed suicide.”

 ”Fluoxetine and similar antidepressant drugs, such as Paroxetine and Sertraline, have seen a significant increase in use over the last decade. Joseph Glen-mullen, Ph.D., author of Prozac Backlash, considers this trend both dangerous and reckless, pointing out that anti-depressants can have severe side effects. These include uncontrollable facial and body tics (which can be signs of severe neurological damage), hallucinations, dizziness, nausea, anxiety, withdrawal symptoms, sexual dysfunction, and electric shock-like sensations in the brain. Dr. Glen-mullen cautions that a small percentage of people can become homicidal, suicidal, or both as a result of Fluoxetine use.”

 For more details regarding this topic, please read.

Some critical side effects of Losartan


Losartan is an oral drug that belongs to the drug class called angiotensin receptor blockers (ARBs).  It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

It is prescribed for the treatment of hypertension. It is also used to lower the risk of stroke in certain people with heart disease.

Important information about losartan

Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Losartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control.

In rare cases, losartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Call your doctor at once if you have any of these symptoms after taking losartan:

  • pain or burning when you urinate;
  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • wheezing, chest pain;
  • drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting;
  • swelling, weight gain, feeling short of breath, urinating less than usual or not at all; or
  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling).
  • a feeling that you might pass out;

Statins Therapy Update- Rhabdomylosis


“Statins” is a class of drugs that lowers the level of cholesterol in the blood by reducing the production of cholesterol by the liver. Statins block the enzyme in the liver that is responsible for making cholesterol. 

The most common side effects are

  • headache,
  • nausea,
  • vomiting,
  • constipation,
  • diarrhea,
  • rash,
  • weakness, and
  • muscle pain. 

The most serious side effects are liver failure and rhabdomyolysis. Rhabdomyolysis is a rare serious side effect which involves damage to muscles. Rhabdomyolysis often begins as muscle pain and can progress to loss of muscle cells, kidney failure, and death. It occurs more often when statins are used in combination with other drugs that themselves cause rhabdomyolysis or with drugs that prevent the elimination of statins and raise the levels of statins in the blood. Since rhabdomyolysis may be fatal, unexplained joint or muscle pain that occurs while taking statins should be brought to the attention of a health care professional for evaluation. Statins must not be used during pregnancy because of the risk of serious adverse effects to the developing fetus. 

With which drugs do statins interact? 

Statins have some important drug interactions. The first type of interaction involves the enzymes responsible for the elimination of statins by the liver. Liver enzymes (specifically, the cytochrome P-450 liver enzymes) are responsible for eliminating all statins from the body with the exception of pravastatin and rosuvastatin. Therefore, drugs that block the action of these liver enzymes increase the levels of simvastatin, lovastatin, fluvastatin, and atorvastatin (but not pravastatin or rosuvastatin) in the blood and can lead to the development of rhabdomyolysis. Drugs or agents that block these enzymes include: 

  • protease inhibitors (for example, indinavir, ritonavir used in treating AIDS,
  • erythromycin,
  • itraconazole,
  • clarithromycin,
  • telithromycin
  • cyclosporine
  • boceprevir
  • telaprevir
  • voriconazole
  • diltiazem,
  • verapamli and
  • grapefruit juice

Weird Side Effect of Drugs: Colored Urine


Rainbow urination might sound kind of cool. But in some cases, if your urine is any color other than clear, yellow or yellowish-orange, you could have something seriously wrong with you. Very dark orange, reddish or brown urine, for example, probably has blood in it and could indicate an infection. Some prescription drugs, though, can turn your urine different colors just by virtue of passing through your system. Red urine can also be caused by taking drugs such as phenazopyridine, used to treat urinary tract infection pain, or deferoxamine, used to treat iron poisoning.

Here are some other potential urine colors and some of the drugs that can cause them:

  • Black – can result from taking Flagyl (generic name metronidazole), furazolidone and several other antibiotics. Aldomet (generic name methyldopa), used to treat high blood pressure in pregnant women, can make urine appear to be black because it darkens upon contact with bleach — often used to clean toilet bowls.
  • Purple – can be a side effect of taking phenolphthalein, used for a long time as a laxative but falling out of favor due to concerns that it may cause cancer [source: Melville].
  • Green – can result from taking Elavil (generic name amitriptyline hydrochloride), an antidepressant also used to treat bed-wetting in children, or Robaxin (generic name methocarbamol), a muscle relaxant used to treat muscle spasms.
  • Blue – can be a side effect of taking Dyrenium (generic name tariamterene), a diuretic, or methylene blue, a chemical compound used in medications like Urised to help reduce irritation caused by bladder infections